Education

ASIC Monthy Webinar

Every month we hold a webinar featuring one of our members. This hour-long event highlights the latest research, mostly unpublished, in intercellular communication.

ASIC Member’s Recent Publications

Identification of state-specific proteomic and transcriptomic signatures of microglia-derived extracellular vesicles

Alterations in Abundance and Compartmentalization of miRNAs in Blood Plasma Extracellular Vesicles and Extracellular Condensates during HIV/SIV Infection and Its Modulation by Antiretroviral Therapy (ART) and Delta-9-Tetrahydrocannabinol (Δ9-THC)

SIV Infection Regulates Compartmentalization of Circulating Blood Plasma miRNAs within Extracellular Vesicles (EVs) and Extracellular Condensates (ECs) and Decreases EV-Associated miRNA-128

Retroviral b-Zip protein (HBZ) contributes to the release of soluble and exosomal immune checkpoint molecules in the context of neuroinflammation

Proteomic Profiling Reveals Distinct Bacterial Extracellular Vesicle Subpopulations with Possibly Unique Functionality

Intermittent systemic exposure to lipopolysaccharide-induced inflammation disrupts hippocampal long-term potentiation and impairs cognition in aging male mice

Towards a human brain EV atlas: Characteristics of EVs from different brain regions, including small RNA and protein profiles

Horizontal Transfer of Malignant Traits and the Involvement of Extracellular Vesicles in Metastasis

Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound

The human neurosecretome: extracellular vesicles and particles (EVPs) of the brain for intercellular communication, therapy, and liquid-biopsy applications

HIV-1-induced nuclear invaginations mediated by VAP-A, ORP3, and Rab7 complex explain infection of activated T cells

Immunopathology of Extracellular Vesicles in Macrophage and Glioma Cross-Talk

Rapid Activation of Neuroinflammation in Stroke: Plasma and Extracellular Vesicles Obtained on a Mobile Stroke Unit

Mitochondrial DNA and inflammatory proteins are higher in extracellular vesicles from frail individuals

Blood plasma derived extracellular vesicles (BEVs): particle purification liquid chromatography (PPLC) and proteomic analysis reveals BEVs as a potential minimally invasive tool for predicting response to breast cancer treatment

Chronic delta-9-tetrahydrocannabinol (THC) treatment counteracts SIV-induced modulation of proinflammatory microRNA cargo in basal ganglia-derived extracellular vesicles

Can Soluble Immune Checkpoint Molecules on Exosomes Mediate Inflammation?

Comparative electrokinetic properties of extracellular vesicles produced by yeast and bacteria

Conference report for the 2nd annual American Society for Intercellular Communication (ASIC) meeting, 2022

Extracellular vesicles in reproduction and pregnancy

A report on ASIC2021: a conference on extracellular vesicle communication mechanisms

Crosstalk Between Autophagy and Nutrigenomics in Neurodegenerative Diseases

Size Exclusion Chromatography for Separating Extracellular Vesicles from Conditioned Cell Culture Media

Cigarette smoke-induced extracellular vesicles from dendritic cells alter T-cell activation and HIV replication

miR-146a Dysregulates Energy Metabolism During Neuroinflammation

Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells

Anti-Human CD9 Fab Fragment Antibody Blocks the Extracellular Vesicle-Mediated Increase in Malignancy of Colon Cancer Cells

HIV-1 Tat and cocaine impact astrocytic energy reservoirs and epigenetic regulation by influencing the LINC01133-hsa-miR-4726-5p-NDUFA9 axis

A secretory form of Parkin-independent mitophagy contributes to the repertoire of extracellular vesicles released into the tumour interstitial fluid in vivo

Regulation of human T-cell leukemia virus type 1 antisense promoter by myocyte enhancer factor-2C in the context of adult T-cell leukemia and lymphoma

Methamphetamine Induces the Release of Proadhesive Extracellular Vesicles and Promotes Syncytia Formation: A Potential Role in HIV-1 Neuropathogenesis

Cannabinoids Reduce Extracellular Vesicle Release from HIV-1 Infected Myeloid Cells and Inhibit Viral Transcription

HIV-1 Tat and cocaine coexposure impacts piRNAs to affect astrocyte energy metabolism

Retroviral infection of human neurospheres and use of stem Cell EVs to repair cellular damage

Extracellular vesicles carry distinct proteo-transcriptomic signatures that are different from their cancer cell of origin

Glioblastoma Extracellular Vesicle-Specific Peptides Inhibit EV-Induced Neuronal Cytotoxicity

Association of extracellular vesicle inflammatory proteins and mortality

Influences of age, race, and sex on extracellular vesicle characteristics

The Past, the Present, and the Future of the Size Exclusion Chromatography in Extracellular Vesicles Separation

HIV-infection and cocaine use regulate semen extracellular vesicles proteome and miRNAome in a manner that mediates strategic monocyte haptotaxis governed by miR-128 network

Differential Packaging Into Outer Membrane Vesicles Upon Oxidative Stress Reveals a General Mechanism for Cargo Selectivity

The extracellular vesicle generation paradox: a bacterial point of view

Microbial vesicle-mediated communication: convergence to understand interactions within and between domains of life

Intermittent Lipopolysaccharide Exposure Significantly Increases Cortical Infarct Size and Impairs Autophagy

IFIT3 (interferon induced protein with tetratricopeptide repeats 3) modulates STAT1 expression in small extracellular vesicles

Itraconazole inhibits nuclear delivery of extracellular vesicle cargo by disrupting the entry of late endosomes into the nucleoplasmic reticulum

Exosomes originating from infection with the cytoplasmic single-stranded RNA virus Rift Valley fever virus (RVFV) protect recipient cells by inducing RIG-I mediated IFN-B response that leads to activation of autophagy

A comprehensive review of COVID-19 biology, diagnostics, therapeutics, and disease impacting the central nervous system

Cocaine augments neuro-inflammation via modulating extracellular vesicle release in HIV-1 infected immune cells

HIV-1 Tat and cocaine impact astrocytic energy reservoir influence on miRNA epigenetic regulation

Extracellular Vesicles from Infected Cells Are Released Prior to Virion Release

Autophagy in Human T-Cell Leukemia Virus Type 1 (HTLV-1) Induced Leukemia

The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection

Exosomes for mRNA delivery: a novel biotherapeutic strategy with hurdles and hope

Extracellular vesicles from HTLV-1 infected cells modulate target cells and viral spread

Exosomes as A Next-Generation Diagnostic and Therapeutic Tool in Prostate Cancer

Mitochondrial DNA in extracellular vesicles declines with age

Dynamin-related Irgm proteins modulate LPS-induced caspase-11 activation and septic shock

Staphylococcus aureus secretes immunomodulatory RNA and DNA via membrane vesicles

Exosome mimicry by a HAVCR1-NPC1 pathway of endosomal fusion mediates hepatitis A virus infection

Hitting the Bullseye: Are extracellular vesicles on target?

Methods for extracellular vesicle isolation from cancer cells

Small extracellular vesicles modulated by αVβ3 integrin induce neuroendocrine differentiation in recipient cancer cells

Small Extracellular Vesicle Regulation of Mitochondrial Dynamics Reprograms a Hypoxic Tumor Microenvironment

The αvβ6 integrin in cancer cell-derived small extracellular vesicles enhances angiogenesis

Uptake and Fate of Extracellular Membrane Vesicles: Nucleoplasmic Reticulum-Associated Late Endosomes as a New Gate to Intercellular Communication

Hitting the Bullseye: Are extracellular vesicles on target?

Extracellular vesicles in diabetes mellitus induce alterations in endothelial cell morphology and migration