| PAR | Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R01, PAR-19-070) (R21, PAR-19-071), Notice to Specify High-Priority Research Topic (NOT-AG-18-047, NOT-AG-18-046, NOT-AG-18-052, NOT-AG-18-048) | 11/13/2024 | NIA | Sanoj K. Suneja, Roderick Corriveau | Mar, Jul, Nov | Resub. |
| PAR | Research on Current Topics in Alzheimer’s Disease and Its Related Dementias (R01 Clinical Trial Optional) (PAR-22-093, PAR-22-094) | 11/13/2024 | NIA, NINDS | Sanoj K. Suneja, Roderick Corriveau | Mar, Jul, Nov | Resub. |
| PAR | Global Brain and Nervous System Disorders Research Across the Lifespan (R01, PAR-22-097, PAR-22-098) | 12/10/2024 | | | | |
| PA | Joint NINDS/NIMH Exploratory Neuroscience Research Grant (R21, PA-21-219) | 01/08/2025 | NINDS/NIMH | | | |
| BPN | Biologic-Based Drug Discovery and Development for Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional) (PAR-21-163, PAR-21-233) | 01/27/2025 | NINDS, NEI, NIA, NIAAA, NIBIB, NICHD, NIDCR, NIDA, NIMH, NCCIH, OBSSR | Multiple POs | Aug, Feb | Resub. |
|
Developing Regulated Therapeutic and Diagnostic Solutions for Patients Affected by Opioid and/or Stimulants use Disorders (OUD/StUD) (R41/R42 Clinical Trial Optional) | 02/15/2025
(R41/R42 and R43/44) | NIDA | Leonardo Angelone, PhD
Tam Nguyen, PhD | | |
| RFA | Role of T-Cells in HIV CNS Reservoir Seeding, Persistence, and Neuropathogenesis (R21 Clinical Trial Not Allowed) | 3/19/2025 | NIMH, NIDA, NINDS | Jeymohan Joseph, Kathleen Ruth Borgmann, William Daley | | |
| PAR | Development of Biomarkers or Biomarker Signatures for Neurological and Neuromuscular Disorders (R61/R33 Clinical Trial Optional) (PAR-22-089) | 05/08/2025 | NIA, NINDS | Carol Taylor-Burds, Yuan Luo | Jun, Feb | Resub. |
| PAR | Technology Development Research for Establishing Feasibility and Proof of Concept (R21 - Clinical Trial Not Allowed) (PAR-22-126)/a> | 05/08/2025 | NIGMS, NCI, NIA | Alvin Yeh, Kadir Aslan, Piotr Grodzinski, Miguel R. Ossandon, Leonid Tsap | Feb, Jun, Oct | Resub. |
| PAR | Focused Technology Research and Development (R01 Clinical Trial Not Allowed) (PAR-22-127) | 05/08/2025 | NIGMS, NCI, NIA | Alvin Yeh, Kadir Aslan, Piotr Grodzinski, Miguel R. Ossandon, Leonid Tsap | Feb, Jun, Oct | Resub. |
| PAR | Prospective Observational Comparative Effectiveness Research in Clinical Neurosciences (UG3/UH3, PAR-22-076) | 05/08/2025 | | | | |
| Focused Technology Research and Development (R01 - Clinical Trial Not Allowed) | 05/08/2025 | | | | |
| PAR | Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (UT1/UT2) Clinical Trial Not Allowed (PAR-23-268) | 06/07/2025 | NCATS | Christine Happel, Meena Rajagopal | Jun | Resub. |
| NOSI | Utilization of Cohorts and Prospective Study Designs for Liquid Biopsy Assay Validation for Early Detection of Cancers | 07/02/2025 | NCI | Matthew Young, Leah E. Mechanic, Xing-Jian Lou | Multiple PARs | |
| Avenir Award Program for Chemistry and Pharmacology of Substance Use Disorders (DP1- Clinical Trial Not Allowed) | 08/08/2025 | NIDA | Sam Ananthan, PhD | | |
| Ex Vivo Models for Studies at the Intersection of HIV and Poly-Substance Use (R01 Clinical Trial Not Allowed) | 08/14/2025 | NIDA | Da-Yu Wu, PhD | | |
| Microglial Pathophysiology in Comorbid Substance Use Disorder (SUD) and HIV (R61/R33 Clinical Trial Not Allowed) | 08/14/2025 | NIDA | Tristan McClure-Begley, PhD | | |
| RFA | Exploratory studies to investigate mechanisms of HIV infection, replication, latency, and/or pathogenesis in the context of substance use disorders (R01 Clinical Trial Not Allowed) | 08/15/2025 | NIDA | Shang-Yi Anne Tsai, Kathleen Borgmann | Aug | Resub. |
| PAS | Advancing Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (R43/R44 Clinical Trial Optional) | 09/06/2025 | NIA, NINDS | Zane Martin, Michael-David ARR Kerns, Annette Gilchrist | Sep, Jan, Apr | Resub. |
| PAR | Precision Approaches in Radiation Synthetic Combinations (PAIRS, R21 Clinical Trial Optional)https://grants.nih.gov/grants/guide/pa-files/PAR-22-199.html | 09/07/2025 | NCI | | | |
| PA | Innovative Approaches to Studying Cancer Communication in the New Information Ecosystem (R21 Clinical Trial Optional) | 9/8/2025 | NCI | Kelly D. Blake | | |
| NOSI | Studies of Cellular/Molecular Pathobiological Mechanisms of Lung Diseases Using Human 3-Dimensional Cellular Systems (R01) | 09/08/2025 | NHLBI | Qing Lu | Standard | Resub. |
| PAR | Bioengineering Research Grants (BRG) (R01 Clinical Trial Not Allowed) | 09/08/2025 | NCI, NEI, NIAMS, NIDCD, NIDCR, NINDS | Multiple POs | Feb, Jun, Oct | Resub. |
| Studies of Cellular/Molecular Pathobiological Mechanisms of Lung Diseases Using Human 3-Dimensional Cellular Systems (R01) | 09/08/2025 | NHLBI | Qing Lu, Ph.D. | Standard | Resub. allowed |
| PAR | Secondary Analysis of Existing Datasets in Heart, Lung, and Blood Diseases and Sleep Disorders (R21 Clinical Trial Not Allowed) | 1/8/2026 | NHLBI | Ruth Kirby | | |
| RFA | Single Cell Opioid Responses in the Context of HIV (SCORCH) Program: Data Mining and Functional Validation (R01 Clinical Trial Not Allowed) | 3/20/2026 | NIDA | John Satterlee | | |
| PAR | NIH SIREN Neurologic Clinical Trials (UG3/UH3 - Clinical Trial Required) | 05/07/2026 | NINDS | | | |
| PAR | Analytical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U01 Clinical Trial Optional) | 06/23/2026 | NINDS | Carol Taylor-Burds | Mar, Jun, Feb | Resub. |
| PAR | Clinical Validation of a Candidate Biomarker for Neurological or Neuromuscular Disorders (U01 Clinical Trial Optional) (PAR-24-097, PAR-24-096) | 06/23/2026 | NINDS | Carol Taylor-Burds | Marc, Jun, Feb | Resub. |
| RFA | BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24, RFA-MH-25-105) | 07/2/2026 | | | | |
| BPN | Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional) | 08/19/2026 | NINDS, NEI, NIA, NIAAA, NIDCR, NIDA, NIMH, NCCIH, OBSSR | Multiple POs | Feb, Jul, Jan | Resub. |
| NOSI | Neuropathogenesis of CNS Complications Associated with HIV | 09/08/2026 | NIMH, NINDS | Vasudev R Raom, William Daley | | |
| NOSI | Clinical Studies of CNS Complications in People with HIV | 09/08/2026 | NIMH, NINDS | Vasudev R Raom, William Daley | | |
| PAR | Cellular and Molecular Biology of Complex Brain Disorders (R01 Clinical Trial Not Allowed) | 9/8/2026 | NIMH | David Panchision | Mar, July, Nov | |
| PAR | Cellular and Molecular Biology of Complex Brain Disorders (R21 Clinical Trial Not Allowed) | 9/8/2026 | NIMH | David Panchision | Mar, July, Nov | |
| NOT | Notice of Special Interest (NOSI): Leveraging glial cells to treat addiction | 9/8/2026 | NIDA | Shang-Yi Anne Tsai | | |
| PAR | Research Projects to Enhance Applicability of Mammalian Models for Translational Research (R01 Clinical Trial Not Allowed) | 9/8/2026 | NCI | Joanna Watson, Christine Nadeau | Mar, July, Nov | |
| PAR | Cellular and Molecular Biology of Complex Brain Disorders (R01 Clinical Trial Not Allowed) | 9/8/2026 | NIMH | David Panchision | Mar, July, Nov | |
| PAR | Cellular and Molecular Biology of Complex Brain Disorders (R21 Clinical Trial Not Allowed) | 9/8/2026 | NIMH | David Panchision | Mar, July, Nov | |
| NOSI | Eradication of HIV-1 from Central Nervous System Reservoirs | 09/09/2026 | NIMH, NINDS | Jeymohan Joseph, William Daley | | |
| PAR | NIH StrokeNet Clinical Trials and Biomarker Studies for Stroke Treatment, Recovery, and Prevention (UG3/UH3 Clinical Trial Optional) | 11/20/2026 | NINDS | Scott Janis | Marc, Jun, Oct | Resub. |
| RNA Delivery Technologies to Allow Specific Tissue Target Homing (RNA-DASH) | 01/06/2027 | NIAID, NCATS, NCI | Multiple POs | Standard | Resub. not applicable |
| NOSI | RNA Delivery Technologies to Allow Specific Tissue Target Homing (RNA-DASH) | 01/06/2027 | NIAID, NCATS, NCI | Michael Minnicozzi, Kien Nguyen, Roger Ptak, Xing-Jian Lou, Philip J. ("Pj") Brooks | Sept, Jan, Ap | Resub. |
| NOSI | Advancing Research for Tickborne Diseases (TBDs) | 01/08/2027 | NIAID, NIAMS, NIMH, NINDS | Samuel Perdue, Su-Yau Mao, Sarah H. Lisanby, William Daley | | |
| PAR | Multidisciplinary Studies of HIV/AIDS and Aging (R01 Clinical Trial Optional) (PAR-24-091, PAR-24-092) | 01/08/2027 | NIA, NIAAA, NIAMS, NIDCR, NIDDK, NIDA, NIMH, NINDS, NCI, ORWH | Multiple POs | May, Sep, Jan | Resub. |
| RFA | BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed) | 02/09/2027 | | | | |
| RFA | BRAIN Initiative: Reagent Resources for Brain Cell Type-Specific Access to Broaden Distribution of Enabling Technologies for Neuroscience (U24 Clinical Trial Not Allowed) | 6/16/2027 | NIMH,NCCIH, NEI, NIA, NIAAA, NIBIB, NICHD, NIDA, NIDCD, NINDS | Douglas S. Kim | Feb | |
| NOT | Human Cell Biology of Alzheimer's Disease Genetic Variants | 11/17/2027 | NIA | Amanda DiBattista | | |
| PAR | Targeting Cell Surface HIV Envelope for Cell Elimination (R01 Clinical Trial Not Allowed) | 1/8/2028 | NIAID | Yan Zhou | Jan, May, Sept | |
| PAR | Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed) | 1/8/2028 | NCI | Charles Lin | Mar, July, Nov | |
| PAR | Tobacco, Alcohol, and Cannabis Policy Research for Health Equity (R21 Clinical Trial Optional) | 1/8/2028 | NCI, NIAAA, NIDA, NIMHD,ODP, SGMRO | Multiple Pos | Mar, July, Nov | |
| PAR | Tobacco, Alcohol, and Cannabis Policy Research for Health Equity (R01 Clinical Trial Optional) | 1/8/2028 | NCI, NIAAA, NIDA, NIMHD, ODP, SGMRO | Multiple Pos | Mar, July, Nov | |
| PAR | Targeting Cell Surface HIV Envelope for Cell Elimination (R01 Clinical Trial Not Allowed) | 1/8/2028 | NIAID | Yan Zhou | May, Sept, Jan | |
| PAR | Molecular Imaging of Inflammation in Cancer (R01 Clinical Trial Not Allowed) | 1/8/2028 | NCI | Charles Lin | Mar, July, Nov | |
| NOT | Notice of Special Interest (NOSI): Innovative Interdisciplinary Research on Female Reproductive Aging | 5/8/2028 | NIA | Fei Wang | | |
| PAR | Early Immune System Development and Ontogeny (R01 Clinical Trial Optional) | 1/8/2029 | NICHD | Sai Majji | May, Jan | |
